A
forensic toxicologist looks at toxics in the body. Due to biochemistry, bones
can be looked upon for historical and recent drug history, many animals’ bones
have been tested upon but there are few humans have been studied. They are many techniques have been used
to identify drugs within bones, including ELISA (Enzyme-linked
immunosorbent assay) and liquid gas chromatography. Vitro studies have shown
that drugs that were found in the blood were detected in the bone; however,
there are different concentrations. A case study in 2005 shown that higher
concentration were found when slivers of the bone was incubated in methanol
rather than incubating the whole bone in water. Unfortunately there is little evidence to indicate the
reactivity of the drugs that were extracted by the ELISA.
Whilst
using anima models, vitro experiments have shown that most drug detections have
a variation with bone type and concentration found. Higher levels of drugs are
commonly found in spongy bone. Decomposition could also effect the concentration
of drugs.
There
is little research on drug detection in skeletal tissues after burial except
for one case were it was impossible to tell weather the drugs were pharmaceutical
or from heroin. ELIZA has been investigating the detection in bone tissue
rather than bone.
Looking
forward more research is needed if the class of drug impacts the timing for it
to be absorbed by the bone. When the bones are buried does the surrounding
factors alter the concentration of drugs with in the bone?
Testing
whether drugs are found in bones will help solve many crimes and indicated if
the cause of death was drug related even if a skeleton remains. If more research is conducted, then
there is a greater chance of identifying a skeleton by looking at the
concentration of drugs that remain in their bones. Also, if environmental influences
affect the levels of toxicology then examining the bones can report can help
determine time of death.
Overall I thought the
article was well written but I wished there was more evidence to support some
of the facts. The article could have been improved if the authors conducted
their own experiments rather then just saying there is little evidence or no
evidence.
Gautam,
Lata, Claire Newland, and Michael D. Cole. "Forensic Magazine." Forensic
Magazine. N.p., 07 Mar. 2013. Web. 12 Oct. 2013.
http://www.forensicmag.com/articles/2013/07/drugs-unusual-matrices-using-bone-tissue-forensic-toxicology-specimen#.Ullrkj17Tao