Mairead Cain
Mr. Ippolito
A/B Odd
16 March 2018
Center for Genomic Regulation. "Gene expression patterns may help determine time of death."
ScienceDaily. ScienceDaily, 13 February 2018.
<www.sciencedaily.com/releases/2018/02/180213132941.htm>
ScienceDaily. ScienceDaily, 13 February 2018.
<www.sciencedaily.com/releases/2018/02/180213132941.htm>
For my current event article, I decided to read and analyze the article “Gene expression
patterns may help determine time of death,” from the online news source Science
Daily. The article discusses the discovery in which scientists can see the time of
death of an individual by examining the changed gene expressions. The scientists
involved are able to examine tissue samples from the deceased and determine the
time of death of said individual with strikingly good accuracy. The study is being
led by Roderic Guigó at the Center for Genomic Regulation. The study led the
researchers involved to use the GTEx system. The GTEx system is one that,
“aimed at creating a reference database and tissue bank for scientists to study how
genomic variants affect gene activity and disease susceptibility.” The GTEx was
useful as it provided the scientists involved with reference samples. Roderic
Guigó and his team were able to find out about the change in gene expression after
death by thoroughly examining RNA-sequencing data from approximately 7,000
samples. “We found that many genes change expression over relatively short
post-mortem intervals, in a largely tissue specific manner. This information
helps us to better understand variation and also it allows us to identify the
transcriptional events triggered by death in an organism,” mentioned Pedro G.
Ferreira, a scientist working on the study.
patterns may help determine time of death,” from the online news source Science
Daily. The article discusses the discovery in which scientists can see the time of
death of an individual by examining the changed gene expressions. The scientists
involved are able to examine tissue samples from the deceased and determine the
time of death of said individual with strikingly good accuracy. The study is being
led by Roderic Guigó at the Center for Genomic Regulation. The study led the
researchers involved to use the GTEx system. The GTEx system is one that,
“aimed at creating a reference database and tissue bank for scientists to study how
genomic variants affect gene activity and disease susceptibility.” The GTEx was
useful as it provided the scientists involved with reference samples. Roderic
Guigó and his team were able to find out about the change in gene expression after
death by thoroughly examining RNA-sequencing data from approximately 7,000
samples. “We found that many genes change expression over relatively short
post-mortem intervals, in a largely tissue specific manner. This information
helps us to better understand variation and also it allows us to identify the
transcriptional events triggered by death in an organism,” mentioned Pedro G.
Ferreira, a scientist working on the study.
Considering the fact that this article concerns the study of determining the exact
time of death, it is very important to the world of forensic science. If the method
is perfected and dispersed among law enforcement institutions across the world,
then the processes of determining the time of death will become much easier. This
can lead to quicker arrests and more trustworthy evidence to be offered during court
trials. It would also surely lead to a safer world as arrests would be much more
definite and conclusive. Despite this, it is evident that the system still has a long
way to go before it will be properly introduced into the world of forensic investigation.
time of death, it is very important to the world of forensic science. If the method
is perfected and dispersed among law enforcement institutions across the world,
then the processes of determining the time of death will become much easier. This
can lead to quicker arrests and more trustworthy evidence to be offered during court
trials. It would also surely lead to a safer world as arrests would be much more
definite and conclusive. Despite this, it is evident that the system still has a long
way to go before it will be properly introduced into the world of forensic investigation.
Overall, I believe that the article “Gene expression patterns may help determine
time of death,” from the online news source Science Daily was extremely well
written and equally informative. The authors were able to describe the complicated
and advanced system developed while relating back to it’s uses and how it could
deeply change the world of forensic science. The authors go into amazing detail
surrounding the exact functions and why the system needs further development
before it will be properly introduced into the world of forensic science. In an effort
to improve the article, the authors should have supplied the reader with more
information concerning how the process literally works. It would have been
interesting to know when exactly the researchers estimate the system will be
introduced after further testing and trials. The authors could have also further
improved the article by describing the ideas behind the creation of the process
and how, exactly, it came to be.
time of death,” from the online news source Science Daily was extremely well
written and equally informative. The authors were able to describe the complicated
and advanced system developed while relating back to it’s uses and how it could
deeply change the world of forensic science. The authors go into amazing detail
surrounding the exact functions and why the system needs further development
before it will be properly introduced into the world of forensic science. In an effort
to improve the article, the authors should have supplied the reader with more
information concerning how the process literally works. It would have been
interesting to know when exactly the researchers estimate the system will be
introduced after further testing and trials. The authors could have also further
improved the article by describing the ideas behind the creation of the process
and how, exactly, it came to be.
6 comments:
Isabella Dibbini
Mr. Ippolito
Forensics
March 16, 2018
Center for Genomic Regulation. "Gene expression patterns may help determine time of death."
ScienceDaily. ScienceDaily, 13 February 2018.
www.sciencedaily.com/releases/2018/02/180213132941.htm
Mairead wrote an excellent review of the article “Gene expression patterns may help determine time of death,” from the online news source Science Daily. Mairead developed an accurate summary of this article. In addition, she incorporated lots of details and statistical evidence to support her claims. For instance, she states “Roderic Guigó and his team were able to find out about the change in gene expression after death by thoroughly examining RNA-sequencing data from approximately 7,000 samples.” Lastly, she includes evidence from the article to support her arguments.
Mairead wrote a very good review on this article, however, there are a few places in which she can improve. To start with, I wish Mairead incorporated more quotes from the article into her review. Also, if Mairead wanted to take her review to the next level, she could include outside research, which would also make her review more interesting.
By reading her review on the article “Gene expression patterns may help determine time of death,” from the online news source Science Daily, I expanded my knowledge on forensic science. Prior to reading this review, I was unaware of this topic. Overall, Mairead’s review is very good and shows a great understanding of this article.
YiFei Wu
Mr. Ippolito
Forensics
3/16/2018
Center for Genomic Regulation. "Gene expression patterns may help determine time of death."
ScienceDaily. ScienceDaily, 13 February 2018.
www.sciencedaily.com/releases/2018/02/180213132941.htm
Mairead Cain wrote an excellent review of the article “Gene expression patterns may help determine time of death,” from the online news source Science Daily. She did an amazing job on summarize the article. I can see clear thoughts from her. Mairead also develops great detail and data to support her claim. “Roderic Guigó and his team were able to find out about the change in gene expression after death by thoroughly examining RNA-sequencing data from approximately 7,000 samples. “We found that many genes change expression over relatively short post-mortem intervals, in a largely tissue specific manner. This information helps us to better understand variation and also it allows us to identify the transcriptional events triggered by death in an organism,” mentioned Pedro G. Ferreira, a scientist working on the study.” This quote from the original post illustrate how detailed Mairead Cain dig into the post and have her thoughts as well as have the evidence to support her claim.
Mairead Cain wrote an awesome review and summary on the article, but there’s still several ways to improve. She might research more and put more outside information into her article and add some author’s quotes in the article will make the article even more interesting.
Overall, Cain did a great job on reviewing this article and it actually can relate to our daily life. I never know this topic until Cain reviewed it. I love this review and she did an amazing job.
Kelsey Ravesloot
Center for Genomic Regulation. "Gene expression patterns may help determine time of death."
ScienceDaily. ScienceDaily, 13 February 2018.
www.sciencedaily.com/releases/2018/02/180213132941.htm
Mairead wrote a review on the article, “Gene expression patterns may help determine time of death”. I thought this was a very well written review and very interesting to read. I liked how she included a lot of details about what is happening with this new possible discovery. Including a lot of details can make the information easier to understand for the reader. I also liked how she included quotes in her review to bring in more direct facts from the article. I also think that Mairead did a great job stating evidence that support her claim.
Although Mairead did a great job on this review, there were a couple things that I wish she included. For example, I wish she included some outside information about this topic because it is so relevant to society.
Overall I think Mairead’s review was very interesting and well written. I think the fact that gene expression patterns could possibly help determine time of death is very fascinating and I would definitely want to read more about this topic in the future.
This week my classmate Mairead Cain did a current event on "Gene expression patterns may help determine time of death." which was written and published by ScienceDaily. The article talks about how investigators can can see the time of death of an individual by examining the changed gene expressions in their DNA.The first thing that surprised me was that they could use the RNA of the tissue to test for the time of death. The test is called GETx. This also surprised me because of how accurate the test can be. Finally, it’s good that the tests could lead to quicker arrests and stronger evidence.
This article was very well written. However, there were two things that Mairead could've added to her article to make it more comprehensible to the reader. The first thing that she could have added was how the GETx tests work. She says the time of death can be found out from the RNA from the tissue, but didn't go into specifics. Lastly, I think she could have included background research to help the reader understand how this test got found out. However, the review was still very interesting and informative.
I think it's always important that we update and try to figure out new ways to help us expand upon our techniques and technology for forensic investigations. These tests with RNA are helping us improve and create stronger evidence to help the courts convicting criminals. This article was very informative and I will look into new forensic techniques when I write current events.
I thought Mairead did a good job of using quotes in her article, since it helped clarify some of the more confusing concepts about this new scientific process. I also thought she made some very good points in her critique of the article, and suggested some things that I never would have thought of. Another thing she did very well is tying the article to the field of forensics in general and explaining its significance.
I think one thing Mairead could have done better in her review is go into a bit more detail in the summary. She says that the article had a lot of detail regarding the functions of the new system and why it still has a long way to go, but she doesn’t mention many of these specifically in the first paragraph. I think more explanation in the summary would make the process being discussed a little easier to understand.
I was very surprised to learn that gene expression changes after death, since we tend to think of genes as something you’re stuck with that can’t be changed, so the idea that they can change on their own when someone isn’t even alive anymore was pretty astonishing.
Jack Baxter
Forensics
3/26/18
Current event comment
Center for Genomic Regulation. "Gene expression patterns may help determine time of death."
ScienceDaily. ScienceDaily, 13 February 2018.
www.sciencedaily.com/releases/2018/02/180213132941.htm
Mairead Cain wrote an excellent review of the article “Gene expression patterns may help determine time of death,” from the online news source Science Daily. She did an amazing job on summarize the article. I can see clear thoughts from her. Mairead also develops great detail and data to support her claim. “Roderic Guigó and his team were able to find out about the change in gene expression after death by thoroughly examining RNA-sequencing data from approximately 7,000 samples. “We found that many genes change expression over relatively short post-mortem intervals, in a largely tissue specific manner. This information helps us to better understand variation and also it allows us to identify the transcriptional events triggered by death in an organism,” mentioned Pedro G. Ferreira, a scientist working on the study.” This quote from the original post illustrate how detailed Mairead Cain dig into the post and have her thoughts as well as have the evidence to support her claim.
Mairead Cain wrote an awesome review and summary on the article, but there’s still several ways to improve. She might research more and put more outside information into her article and add some author’s quotes in the article will make the article even more interesting.
Overall, Cain did a great job on reviewing this article and it actually can relate to our daily life. I never know this topic until Cain reviewed it. I love this review and she did an amazing job.
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